American CDMO Solutions that Serve Science and Our Nation.
Phlow is the modern, small molecule API development and manufacturing organization that is driving sustainable cost competitiveness, restoring America’s pharmaceutical sovereignty, and strengthening U.S. national preparedness.

What We Do
U.S. Capacity Turned On.
One Timezone, Built to Scale.
Process Research & Development and Analytical Laboratories
Early-stage process development and analytical support to enable smooth scale-up.

Kilo-Scale cGMP Facility
Flexible, small-batch production to support preclinical and clinical development.

Metric Ton-Scale cGMP Facility
High-volume, commercial-ready manufacturing with the highest U.S. standards.


Working with Phlow
More than a CDMO—your partner in building a stronger pharmaceutical future for America.
Phlow isn’t just filling capacity—we’re creating the future of how medicines are made. With a mission rooted in public good, modern chemistry, and U.S.-based infrastructure, we help brilliant minds bring medicines to life through advanced development and manufacturing in America. Here’s how we do it:

Real-Time Visibility, Trusted Oversight
With dedicated project management, secure data systems, and operations in a single U.S. time zone, Phlow keeps you connected and informed every step of the way.

Flexible Capacity, Built to Serve
From early-stage development to commercial-scale production, our U.S.-based facilities are designed to meet your project’s unique requirements with speed, quality, and agility.

Advanced Capabilities, American Quality
Our process development and analytical experts leverage modern chemistry, including flow chemistry and other innovative platforms, to accelerate your path to market.
News and Events
Inside the Modern Medicine Movement
From milestones to industry insights, see how Phlow is creating the future of how medicines are made.

Phlow Corp. Selected by the U.S. Food and Drug Administration Commissioner’s First-Ever National Priority Voucher Pilot Program to Advance Manufacturing of a Critical Essential Medicine in America

Phlow Appoints Tim M. Mayleben as Chairman of the Board, Building on Bold Leadership and Expanding America’s Medicine Manufacturing Future

Phlow Observes 5th Annual National Essential Medicine Shortage Awareness Day, Accelerating Efforts to Strengthen America’s Medicine Supply Chain
Reclaiming America’s Pharmaceutical Sovereignty
As America’s modern medicine manufacturer, Phlow is built on the unyielding pursuit of progress—a future forged on U.S. soil and powered by the relentless spirit of American ingenuity. With advanced technology, unwavering purpose, and a world-class team, we’re redefining how medicines are developed and manufactured, and doing that here in the United States.
Phlow’s Story
Born to Solve a Crisis.
Built for Generational Change.
In 2019, Phlow set out to solve a decades-old problem: a broken pharmaceutical supply chain that leaves our country vulnerable to shortages of the medicines that our Nation requires to sustain life and conquer disease.
From the start, we’ve been focused on more than manufacturing. We’re building resilience into the system, creating a modern foundation for how medicines are developed and manufactured in the U.S. with innovation, security, and sustainability at the core.
Phlow has a world-class team modernizing every step of API production from early-stage process development to commercial-scale manufacturing and strategic reserve storage. Together, we’re not just filling a gap; we’re creating the future of how medicines are made.
Our Origin Story

Built with Purpose. Driven by Values.
At Phlow, we believe in doing work that matters. Our culture is rooted in a shared commitment to serve brilliant minds in the pharma industry and Government with excellence, integrity, and care. Our mission guides us. Our values unite us. And our purpose gives us the clarity and courage to keep pushing forward.
Our Purpose
Create the future of how medicines are made.
Our Mission
Help brilliant minds bring medicines to life through advanced development and manufacturing in America.
Our Core Values
Be Relentless
Own Safety & Quality
Demand the Extraordinary
Align & Win
Commit to Excellence
Richmond, Virginia, USA
Phlow Headquarters
Phlow’s HQ is home to leadership, operations, and business functions that support our mission and impact.
Process R&D and Analytical Laboratories
These labs support early-stage development, method validation, and analytical excellence.
Kilo-Scale cGMP Facility
Flexible, small-batch manufacturing to support preclinical and clinical API production.
Metric Ton-Scale cGMP Facility
High-volume API manufacturing to meet commercial and strategic needs.